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SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
USERS' SCORE
Good
Based on 4 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 90
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
250 mcg(10,000 IU)
1250%
Top Medical Research Studies
9
Vitamin D3 lowers cholesterol levels
Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity.
Directly addresses cholesterol effects
We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
Read More
8
Vitamin D3 improves cholesterol levels
The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial.
Directly investigates vitamin D and cholesterol
We conducted a double-blind, randomized clinical trial to investigate how vitamin D3 treatment influences cholesterol levels in patients with ischemic heart disease (IHD) who were also vitamin D deficient. In total, 44 patients participated, and we divided them into two groups: one received vitamin D3 supplements, while the other was given a placebo.
After a five-week treatment period, we observed some interesting results. In the group that received vitamin D3, levels of high-density lipoprotein (often referred to as “good cholesterol”) significantly increased, while triglycerides—a type of fat in the blood—decreased notably. These changes are beneficial as higher HDL levels and lower triglycerides can improve heart health.
These findings highlight the potential for vitamin D3 to play a positive role in managing cholesterol levels among IHD patients. While we noted these improvements in lipid profiles, the correlation between vitamin D levels and C-reactive protein, a marker of inflammation in the body, was not significant in our study, indicating that while vitamin D shows promise, more research is warranted.
After a five-week treatment period, we observed some interesting results. In the group that received vitamin D3, levels of high-density lipoprotein (often referred to as “good cholesterol”) significantly increased, while triglycerides—a type of fat in the blood—decreased notably. These changes are beneficial as higher HDL levels and lower triglycerides can improve heart health.
These findings highlight the potential for vitamin D3 to play a positive role in managing cholesterol levels among IHD patients. While we noted these improvements in lipid profiles, the correlation between vitamin D levels and C-reactive protein, a marker of inflammation in the body, was not significant in our study, indicating that while vitamin D shows promise, more research is warranted.
Read More
9
Vitamin D3 reduces triglycerides and cholesterol
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
Highly relevant to cholesterol management
We evaluated how vitamin D3 supplementation influences cholesterol levels in overweight or obese women through a comprehensive meta-analysis of randomized controlled trials. Our focus was on understanding whether this vitamin could effectively improve lipid profiles, specifically high cholesterol levels.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
Read More
Most Useful Reviews
9.5
Effective treatment
Works!!! The medication is effective! In October 2022, my husband had a Vitamin D test with a level of 14.5 ng/ml, marking a deficiency in our area. After a month of taking this drug, his level rose to 74 ng/ml. We plan to switch to 10,000 IU every five days after reaching 80 ng/ml. This "liposomal" formulation is particularly suitable for individuals with gastrointestinal issues, enhancing absorption! I appreciate the consistent 10,000 IU dosage that isn't common among manufacturers, coupled with the dark glass packaging. If you're seeking a quality outcome swiftly, with minimal risks or side effects, I wholeheartedly recommend this drug!!!
Read More
9.5
Rapid improvement
Attention! This Vitamin D boosted my levels from low to nearly high in just two months!!! If you're hesitant because of the price, cast aside all doubts and order it immediately! Health is paramount. Wishing everyone good luck and a long life!
Read More
8.8
Consistent quality
Very high-quality Vitamin D! It arrived well-packaged and is absorbed well in 10,000 IU doses. I regularly take it to maintain my levels and continuously order it, often with Vitamin K2. Its effectiveness is apparent after a month and it also supports immunity. I recommend this to everyone, especially those with a Vitamin D deficiency.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
9
Vitamin D3 reduces triglycerides and cholesterol
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
Highly relevant to cholesterol management
We evaluated how vitamin D3 supplementation influences cholesterol levels in overweight or obese women through a comprehensive meta-analysis of randomized controlled trials. Our focus was on understanding whether this vitamin could effectively improve lipid profiles, specifically high cholesterol levels.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
Read More
9
Vitamin D3 lowers cholesterol levels
Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity.
Directly addresses cholesterol effects
We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
Read More
9
Vitamin D3 reduces cholesterol imbalance
Vitamin D supplementation is effective for olanzapine-induced dyslipidemia.
Explores vitamin D's cholesterol effects
We explored the impact of vitamin D3 on cholesterol levels, specifically in individuals taking olanzapine, an antipsychotic medication known to cause dyslipidemia, a condition characterized by abnormal lipid levels. By analyzing various sources including the FDA Adverse Event Reporting System and electronic medical records, we aimed to uncover whether vitamin D3 supplementation could alleviate the cholesterol imbalances caused by olanzapine.
Our findings revealed that vitamin D3 has a beneficial effect, helping to reduce the unfavorable changes in cholesterol levels typically induced by olanzapine. In particular, we noted that while olanzapine raised low-density lipoprotein (LDL) cholesterol and lowered high-density lipoprotein (HDL) cholesterol, vitamin D3 supplementation appeared to help restore balance in these lipid levels.
Further investigations into cellular mechanisms showed that vitamin D3 may work by inhibiting the cholesterol production process within certain cells. This aligns well with our overall goal of identifying effective treatment strategies that can positively affect cholesterol management in those affected by olanzapine treatment.
In summary, our comprehensive analysis suggests that vitamin D3 supplementation could serve as a promising adjunct therapy for managing cholesterol levels in patients prescribed olanzapine.
Our findings revealed that vitamin D3 has a beneficial effect, helping to reduce the unfavorable changes in cholesterol levels typically induced by olanzapine. In particular, we noted that while olanzapine raised low-density lipoprotein (LDL) cholesterol and lowered high-density lipoprotein (HDL) cholesterol, vitamin D3 supplementation appeared to help restore balance in these lipid levels.
Further investigations into cellular mechanisms showed that vitamin D3 may work by inhibiting the cholesterol production process within certain cells. This aligns well with our overall goal of identifying effective treatment strategies that can positively affect cholesterol management in those affected by olanzapine treatment.
In summary, our comprehensive analysis suggests that vitamin D3 supplementation could serve as a promising adjunct therapy for managing cholesterol levels in patients prescribed olanzapine.
Read More
8
Vitamin D3 improves cholesterol levels
The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial.
Directly investigates vitamin D and cholesterol
We conducted a double-blind, randomized clinical trial to investigate how vitamin D3 treatment influences cholesterol levels in patients with ischemic heart disease (IHD) who were also vitamin D deficient. In total, 44 patients participated, and we divided them into two groups: one received vitamin D3 supplements, while the other was given a placebo.
After a five-week treatment period, we observed some interesting results. In the group that received vitamin D3, levels of high-density lipoprotein (often referred to as “good cholesterol”) significantly increased, while triglycerides—a type of fat in the blood—decreased notably. These changes are beneficial as higher HDL levels and lower triglycerides can improve heart health.
These findings highlight the potential for vitamin D3 to play a positive role in managing cholesterol levels among IHD patients. While we noted these improvements in lipid profiles, the correlation between vitamin D levels and C-reactive protein, a marker of inflammation in the body, was not significant in our study, indicating that while vitamin D shows promise, more research is warranted.
After a five-week treatment period, we observed some interesting results. In the group that received vitamin D3, levels of high-density lipoprotein (often referred to as “good cholesterol”) significantly increased, while triglycerides—a type of fat in the blood—decreased notably. These changes are beneficial as higher HDL levels and lower triglycerides can improve heart health.
These findings highlight the potential for vitamin D3 to play a positive role in managing cholesterol levels among IHD patients. While we noted these improvements in lipid profiles, the correlation between vitamin D levels and C-reactive protein, a marker of inflammation in the body, was not significant in our study, indicating that while vitamin D shows promise, more research is warranted.
Read More
8
Vitamin D3 and cholesterol reduction
[Vitamin D3 alleviates the gastritis that associated with Helicobacter pylori infection in mice with hypercholesterolemia by enhancing the activity of vitamin D receptors in the liver tissue and blocking the signaling pathway of JAK/STAT3].
Moderate relevance of findings
We investigated whether vitamin D3 could help lower cholesterol and alleviate effects from Helicobacter pylori (Hp) infection in mice with high cholesterol. Through an 8-week oral treatment, we found that vitamin D3 showed promise in enhancing liver function by increasing the activity of vitamin D receptors (VDR) in liver tissues.
Notably, there was a marked decrease in serum cholesterol levels after the treatment. We also observed a reduction in the expression of certain inflammatory markers in the gastric tissues, indicating a potential link between vitamin D3 and inflammation reduction associated with Hp infection.
Furthermore, our findings suggested that vitamin D3 may help manage gastritis symptoms by blocking a specific signaling pathway known as JAK/STAT3. However, while the study demonstrated some beneficial effects, it’s important to note that these results were obtained in a controlled environment and might not directly translate to humans without further research.
Notably, there was a marked decrease in serum cholesterol levels after the treatment. We also observed a reduction in the expression of certain inflammatory markers in the gastric tissues, indicating a potential link between vitamin D3 and inflammation reduction associated with Hp infection.
Furthermore, our findings suggested that vitamin D3 may help manage gastritis symptoms by blocking a specific signaling pathway known as JAK/STAT3. However, while the study demonstrated some beneficial effects, it’s important to note that these results were obtained in a controlled environment and might not directly translate to humans without further research.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.7
9.5
Effective treatment
Works!!! The medication is effective! In October 2022, my husband had a Vitamin D test with a level of 14.5 ng/ml, marking a deficiency in our area. After a month of taking this drug, his level rose to 74 ng/ml. We plan to switch to 10,000 IU every five days after reaching 80 ng/ml. This "liposomal" formulation is particularly suitable for individuals with gastrointestinal issues, enhancing absorption! I appreciate the consistent 10,000 IU dosage that isn't common among manufacturers, coupled with the dark glass packaging. If you're seeking a quality outcome swiftly, with minimal risks or side effects, I wholeheartedly recommend this drug!!!
Read More
9.5
Rapid improvement
Attention! This Vitamin D boosted my levels from low to nearly high in just two months!!! If you're hesitant because of the price, cast aside all doubts and order it immediately! Health is paramount. Wishing everyone good luck and a long life!
8.8
Vitamin D improvement
The only supplement that increased my vitamin D levels! For six years, I struggled to get above 29.7, possibly due to low stomach acidity. Just four days after starting this supplement, I tested again and my Vitamin D rose to 42.5! I'm out of the deficit now and aiming for at least 90. The supplement's quality is exceptional, and the ingredients are effective! I feel much better and the dosage is optimal. I'll re-evaluate soon and update my review.
Read More
8.8
Consistent quality
Very high-quality Vitamin D! It arrived well-packaged and is absorbed well in 10,000 IU doses. I regularly take it to maintain my levels and continuously order it, often with Vitamin K2. Its effectiveness is apparent after a month and it also supports immunity. I recommend this to everyone, especially those with a Vitamin D deficiency.
Read More
